SaxoCell Newsletter Issue No. 4
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September 2022
 

"SaxoPhone" - SaxoCell Newsletter

Our autumn edition delivers the third and final piece in our series of portraying our platforms: SaxoCellClinics.

We are also looking back at our first Stammtisch get-together in person with some great pictures in stock.

Enjoy reading!
Impressions from our Stammtisch in August

Portraying... SaxoCell Clinics

News from our projects

News from our website

Save the date - SaxoCell events

News from industry

News from science

past Events

Upcoming events

 

Impressions from our Stammtisch in August

[© SaxoCell; Participants of our latest Stammtisch meetings in Dresden and Leipzig]
Our first real SaxoCell Stammtisch took place in parallel in Dresden and Leipzig on August 31st and it was great chatting with each other face to face in a comfortable environment!

At CRTD in Dresden, we were invited to listen to two start-up talks and to engange in a lively dicussion about the challenges faced when starting-up. We thank Richard Wetzel from denovoMATRIX as well as Claudia Mende and Robin Stegmann from Lohrmanns Brew for being our guests in Dresden and for spicing up our Stammtisch!

Of course, we also thank all participants in both cities for being there and making this a great afternoon.
 
» Some impressions can be found in our website's members area.
 
» How to access our members area
 

Portraying...

[© SaxoCell; CLINICS]

SaxoCell CLINICS

Offering clinical support for all our innovative SaxoCell research projects as well as bundling the clinical expertise of our three locations Leipzig, Dresden and Chemnitz, SaxoCell Clinics act as interface between research institutes, industry and authorities.
 
» Continue reading
 

News from our projects

[© SaxoCell; MSC-PreStiGe]

MSC-PreStiGe

Coordinated by Mario Rüdiger at the University Clinic in Dresden, the project exploits the immunomodulatory potential of mesenchymal stromal cells (MSC) extracted from umbilical cord tissue.
 
» Continue reading

[© SaxoCell; TheraSTAR]

TheraSTAR

Aiming to develop theranostic targets that significantly support both conventional CAR and universal adapter CAR technologies in our cluster, this project deploys theranostic platform technologies to pave the way for an improved, effective, safe and personalized immunotherapy.
 
» Continue reading
 

News from our Website

[© SaxoCell; Website Members Area]
We have added some more content to our members area, for example:

- Presentation slides from our Kick-off Meeting and Consortium Meeting
- Training materials from our Transfer Workshop sessions 1 & 2

- Company presentations from this year's tradeshow visits
- Current German funding opportunities
- Photos from our Stammtisch sessions
 
» Please visit our members area by following the link.
 

Save the date - SaxoCell trainings and events

October 3rd, 2022
Public event
Türen auf mit der Maus
Discover SaxoCell
Ort CRTD Dresden
» more information

October 11th, 2022
12:30 PM - 2:30 PM
Workshop
Technology Transfer Workshop
- Session 3 "How to cooperate"

Open to all SaxoCell members
Ort Online
» Contact us for registration

October 13th, 2022
4 - 6 PM
Exchange
SaxoCell Stammtisch
Our casual get-together
Ort Dresden & Leipzig
(MORE INFORMATION WILL FOLLOW)

November 11th, 2022
9 AM - 12 PM
Workshop
Be creative - Design Thinking in a nutshell (with Yvonne Horn)
Be creative – shine at a pitch – start a startup
A SaxoCell event series to get your ideas on track
Ort CRTD Dresden
» Contact us for registration

November 25th, 2022
9 AM - 12 PM
Workshop
Shine at a Pitch (with Konrad Sell)
Be creative – shine at a pitch – start a startup
A SaxoCell event series to get your ideas on track
Ort CRTD Dresden
» Contact us for registration

December 9th, 2022
9 AM - 12 PM
Workshop
Start at Startup (with Dorit Teilchmann)
Be creative – shine at a pitch – start a startup
A SaxoCell event series to get your ideas on track
Ort CRTD Dresden
» Contact us for registration

December 2022
(details will be announced)
Exchange
SaxoCell Stammtisch
Our casual get-together
Ort Dresden & Leipzig
(MORE INFORMATION WILL FOLLOW)

March 16th-17th 2023
Workshop
SaxoCell CLINICS Workshop
Training on regulatory processes related to clinical trials
Ort University Hospital Leipzig
» more information will follow
 

News from industry

We have compiled an overview on latest news from industry
in the field of gene and cell therapy.
» News from industry
[© SaxoCell; Industry News]
 

News from science - latest SaxoCell publications

Recent publication from our cluster:

Potential solutions for manufacture of CAR T cells in cancer immunotherapy. Blache et al., Nat Commun. 2022 Sep 5;13(1):5225.

Efficient correction of oncogenic KRAS and TP53 mutations through CRISPR base editing. Sayed et al., Cancer Res. 2022 Jul 8:can.21.2519.

Other interesting publications from our members:

ROR1-targeting switchable CAR-T cells for cancer therapy. Peng et al., Oncogene. 2022 Aug;41(34):4104-4114.

Reproducible measurable residual disease detection by multiparametric flow cytometry in acute myeloid leukemia. Röhnert et al., Leukemia. 2022 Jul 18. doi: 10.1038/s41375-022-01647-5.

Longitudinal outcome over two decades of unrelated allogeneic stem cell transplantation for relapsed/refractory acute myeloid leukemia: an ALWP/EBMT analysis. Nagler et al., Clin Cancer Res. 2022 Jun 7:clincanres.0809.2022-3-14 14:38:43.713. doi: 10.1158/1078-0432.CCR-22-0809.
 
» Please keep us informed on publications from your labs!
 

Events – Retrospect

[© SaxoCell; Long Night of Science at CRTD 2022]

Long Night of Science at CRTD

SaxoCell successfully introduced itself at this year's Long Night of Science in Dresden on 8th July.

We really enjoyed meeting so many curious and interested people of all ages.

Our virus puzzle broke the ice and our DNA cookies were a raving success. We already look forward to next year's event!

SaxoCell Transfer Workshops

Our 3-session workshop series on technology transfer was well perceived by the participants - all from our SaxoCell projects.

Our first session How to transfer in April was a 2-hour workshop which provided compact introduction into technology transfer and related matters including intellectual property, ways of transfer and contracts.

In our second session in July called How to start-up, participants gained insight into the way of starting-up including business planing, financing and support.

Our third session How to cooperate will follow in October. Registrations are still possible (see Save the date section).
[© SaxoCell, Transfer Workshop]

[© SaxoCell; GMP basic course]

GMP Training Courses

In this first year of our cluster, the SaxoCell Hub Team has organised two GMP training courses for SaxoCell members which took place at CRTD in Dresden.

The basic course on 30th June offered a first insight into Good Manufacturing Practice introducing the 15 participants to national and international rules and regulations, to the development of manufacturing processes as well as to documentation and material management.
The advanced course on 22nd September - again presented by GMP Academy - focussed on quality assurance, contamination controls, validation in cell culture and on requirements for consumables for ATMP. It also included a practical session offering hands-on experience.

The feedback we received was very positive and we will certainly stage more courses of this kind. We thank all participants for making this a success!

Public lectures of Uwe Platzbecker & Mario Rüdiger

In our SaxoCell lecture series open to the public, current developments in the field of cell therapy and gene therapy are to be presented by specialists from our cluster and beyond in a clear and understandable way for a broad public.The past two lectures were given by Prof. Uwe Platzbecker and Prof. Mario Rüdiger. The next lecture is scheduled for December.
[© SaxoCell; Prof. Dr. med. Uwe Platzbecker]

Uwe Platzbecker on immunotherapies for blood cancer

On July 11th, Prof. Uwe Platzbecker, Head of the Department for Hematology & Cell Therapy at Leipzig University Hospital gave a lecture on immunotherapies for blood cancer. A total of 35 participants attended the lecture, including PhD students, postdocs, technical assistants and various company representatives. We would like to thank Prof. Platzbecker for his talk and all participants for the lively discussion!
[© SaxoCell; Prof. Dr. med Mario Rüdiger]

Mario Rüdiger on mesenchymal stromal cells

On September 12th, about 40 participants (at CRTD and onlline) followed Prof. Mario Rüdiger's talk on mesenchymal stromal cells and the current state of research taking latest discoveries from the laboratory to the patient. Prof. Mario Rüdiger is head of the Department of Neonatology and Pediatric Intensive Care at Dresden University Hospital.

Torsten Tonn reaching out to the public in Dresden Botanical Garden

In front of over 30 listeners, Prof. Torsten Tonn shared his vision and gave an insight into his work on natural killer cells used as living medicine. He also addressed opportunities this creates for SaxoCell. It was a very fruitful and lively discussion. A podcast version of the event will be available in a few weeks' time.
 
» Link to the podcast
[© SaxoCell; Prof. Dr. med. Torsten Tonn]
 

Events - Preview

Here is a list of upcoming events with SaxoCell participation:
October 6th-7th, 2022
Conference
Australian Society of Molecular Imaging Annual Meeting 2022
SaxoCell project TheraSTAR will be present at event
Ort Melbourne, Australia
» to the event
October 24th-26th, 2022
Meeting
BIO-EUROPE 2022
Europe's largest partnering event for the international biotech and pharmaceutical scene
Ort Leipzig, Germany (hybrid event)
» to the event
November 11th, 2022
Meeting
Shaping the future of Medicine
Formerly 'Shaping the future of Hematology'
Ort Leipzig, Germany (hybrid event)
» to the event
November 22nd-23rd, 2022
Meeting
LION conference 2022
Leipzig Immune ONcology Conference
Ort Online
» TO THE EVENT
December 10th-13th, 2022
Meeting
64th ASH Annual Meeting and Exposition
American Society for Hematology
Ort New Orleans, USA
» TO THE EVENT

If you are interested in more information about any of these events or about the role of SaxoCell at these tradefairs, please do not hesitate to contact us.
 
» Contact us via e-mail

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Contact us

[© SaxoCell]

We'll be happy to hear from you

If you have any questions, suggestions and feedback regarding the newsletter, please feel free to contact the SaxoCell HUB team.
 
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